Pressure pulse transmission into vascular beds

Arnold G. Salotto, Lawrence F. Muscarella, Julius Melbin, John K.J. Li, Abraham Noordergraaf

Research output: Contribution to journalArticle

22 Scopus citations

Abstract

Observations at the microcirculatory level have revealed that (a) the pressure pulse reaches the smallest vessel, and (b) the pulse wave velocity alters from a value in the order of meters/second in large arteries to a value in the order of centimeters/second in the microvessels. We investigate, herein, whether these experimental findings are consonant with linear pulse wave transmission theory in a branching system of vessels. Our computations, utilizing available data, show that this is indeed the case. For low frequency (1 Hz), cumulative attenuation is such that about one-third of the pulse, originating at the heart, reaches the capillary. A 10-Hz pulse, however, is virtually completely attenuated by the time the cpaillary is reached. Transmission time for a pulse, from heart to capillary, is also frequency dependent, with higher frequencies propagating more rapidly. Vasoconstriction, at the arteriolar level in the absence of reflection, can also strongly attenuate the pulse remnant at that site.

Original languageEnglish (US)
Pages (from-to)152-163
Number of pages12
JournalMicrovascular Research
Volume32
Issue number2
DOIs
StatePublished - Sep 1986

All Science Journal Classification (ASJC) codes

  • Biochemistry
  • Cardiology and Cardiovascular Medicine
  • Cell Biology

Fingerprint Dive into the research topics of 'Pressure pulse transmission into vascular beds'. Together they form a unique fingerprint.

  • Cite this

    Salotto, A. G., Muscarella, L. F., Melbin, J., Li, J. K. J., & Noordergraaf, A. (1986). Pressure pulse transmission into vascular beds. Microvascular Research, 32(2), 152-163. https://doi.org/10.1016/0026-2862(86)90051-8