Prevention of pectus excavatum for children with spinal muscular atrophy type 1

John R. Bach, Carlo Bianchi

Research output: Contribution to journalArticle

68 Scopus citations


To demonstrate the elimination of pectus excavatum and promotion of more normal lung growth and chest wall development by the use of high-span positive inspiratory pressure plus positive end-expiratory pressure (PIP+PEEP), patients with spinal muscular atrophy type 1 with paradoxical breathing were placed on high-span PIP+PEEP when sleeping from the point of diagnosis of spinal muscular atrophy. Although the appearance of pectus excavatum is ubiquitous in untreated infants with spinal muscular atrophy type 1, after institution of high-span PIP+PEEP, pectus resolves and lungs and chest walls grow more normally. High-span PIP+PEEP is indicated for all infants diagnosed with spinal muscular atrophy who demonstrate paradoxical breathing for the purpose of promoting more normal lung and chest development.

Original languageEnglish (US)
Pages (from-to)815-819
Number of pages5
JournalAmerican Journal of Physical Medicine and Rehabilitation
Issue number10
StatePublished - Oct 1 2003

All Science Journal Classification (ASJC) codes

  • Physical Therapy, Sports Therapy and Rehabilitation
  • Rehabilitation


  • Mechanical Ventilation
  • Noninvasive Mechanical Ventilation
  • Pectus Excavatum
  • Respiratory Paralysis
  • Spinal Muscular Atrophy

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