Production of collagenase by mouse peritoneal macrophages in vitro characterization of sites of cleavage of tropocollagen

Peter A. Boxer, S. Joseph Leibovich

Research output: Contribution to journalArticlepeer-review

6 Scopus citations

Abstract

Macrophages from mineral oil-stimulated mice produce collagenase at a constant rate over several days in culture. Phagocytosis of latex does not increase production of enzyme. Gel electrophoretic and electron microscopic analyses indicate that the specificity of the macrophage enzyme is similar to that of other previously characterized mammalian collagenases.

Original languageEnglish (US)
Pages (from-to)626-632
Number of pages7
JournalBBA - General Subjects
Volume444
Issue number2
DOIs
StatePublished - Sep 24 1976
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Biophysics
  • Biochemistry
  • Molecular Biology

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