PUPylation Provides the Punch As Mycobacterium tuberculosis Battles the Host Macrophage

Padmini Salgame

doi:10.1016/j.chom.2008.10.009

PUPylation Provides the Punch As Mycobacterium tuberculosis Battles the Host Macrophage

Padmini Salgame

New Jersey Medical School (NJMS), Medicine, Division of Infectious Disease

Research output: Contribution to journal › Short survey › peer-review

6 Scopus citations

Abstract

The proteasome machinery has been shown to provide Mycobacterium tuberculosis (Mtb) with the ability to protect itself from the damaging effects of reactive nitrogen intermediates. In their recent paper, Darwin and colleagues identify the protein modifier in Mtb that targets substrates for degradation in the Mtb proteasome.

Original language	English (US)
Pages (from-to)	415-416
Number of pages	2
Journal	Cell Host and Microbe
Volume	4
Issue number	5
DOIs	https://doi.org/10.1016/j.chom.2008.10.009
State	Published - Nov 13 2008

All Science Journal Classification (ASJC) codes

Parasitology
Microbiology
Virology

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10.1016/j.chom.2008.10.009

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title = "PUPylation Provides the Punch As Mycobacterium tuberculosis Battles the Host Macrophage",

abstract = "The proteasome machinery has been shown to provide Mycobacterium tuberculosis (Mtb) with the ability to protect itself from the damaging effects of reactive nitrogen intermediates. In their recent paper, Darwin and colleagues identify the protein modifier in Mtb that targets substrates for degradation in the Mtb proteasome.",

author = "Padmini Salgame",

note = "Funding Information: This work was supported by National Institutes of Health Grant AI AI055377 and AI069395. The author thanks Wasiulla Rafi and Amanda McBride, members of her laboratory, for helpful comments.",

year = "2008",

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AU - Salgame, Padmini

N1 - Funding Information: This work was supported by National Institutes of Health Grant AI AI055377 and AI069395. The author thanks Wasiulla Rafi and Amanda McBride, members of her laboratory, for helpful comments.

PY - 2008/11/13

Y1 - 2008/11/13

N2 - The proteasome machinery has been shown to provide Mycobacterium tuberculosis (Mtb) with the ability to protect itself from the damaging effects of reactive nitrogen intermediates. In their recent paper, Darwin and colleagues identify the protein modifier in Mtb that targets substrates for degradation in the Mtb proteasome.

AB - The proteasome machinery has been shown to provide Mycobacterium tuberculosis (Mtb) with the ability to protect itself from the damaging effects of reactive nitrogen intermediates. In their recent paper, Darwin and colleagues identify the protein modifier in Mtb that targets substrates for degradation in the Mtb proteasome.

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PUPylation Provides the Punch As Mycobacterium tuberculosis Battles the Host Macrophage

Abstract

All Science Journal Classification (ASJC) codes

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