Qualitative variation of anti-diabetic compounds in different tarragon (Artemisia dracunculus L.) cytotypes

Sasha W. Eisenman, Alexander Poulev, Lena Struwe, Ilya Raskin, David M. Ribnicky

Research output: Contribution to journalArticlepeer-review

30 Scopus citations

Abstract

Ethanolic extracts of diploid Artemisia dracunculus L. (wild tarragon) from populations in the U.S., and polyploid tarragon from a variety of sources, were screened for the anti-diabetic compounds davidigenin; sakuranetin; 2',4'-dihydroxy-4-methoxydihydrochalcone; 4,5-di-O-caffeoylquinic acid; 5-O-caffeoylquinic acid and 6-demethoxycapillarisin using LC-MS. Only decaploid plants contained all six target compounds and were the only plants that contained davidigenin and 2,4-dihydroxy-4-methoxydihydrochalcone. These results exhibit the importance of germplasm selection and provenance when studying plants for medicinal activity. Relying only on the "right species" for consistent medicinal activities may not be sufficient, as intraspecific variation may be highly significant.

Original languageEnglish (US)
Pages (from-to)1062-1074
Number of pages13
JournalFitoterapia
Volume82
Issue number7
DOIs
StatePublished - Oct 2011

All Science Journal Classification (ASJC) codes

  • Pharmacology
  • Drug Discovery

Keywords

  • Artemisia dracunculus
  • Diabetes
  • Germplasm
  • Polyploidy
  • Sakuranetin
  • Wild tarragon

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