TY - JOUR
T1 - RCSB Protein Data Bank (RCSB.org)
T2 - delivery of experimentally-determined PDB structures alongside one million computed structure models of proteins from artificial intelligence/machine learning
AU - Burley, Stephen K.
AU - Bhikadiya, Charmi
AU - Bi, Chunxiao
AU - Bittrich, Sebastian
AU - Chao, Henry
AU - Chen, Li
AU - Craig, Paul A.
AU - Crichlow, Gregg V.
AU - Dalenberg, Kenneth
AU - Duarte, Jose M.
AU - Dutta, Shuchismita
AU - Fayazi, Maryam
AU - Feng, Zukang
AU - Flatt, Justin W.
AU - Ganesan, Sai
AU - Ghosh, Sutapa
AU - Goodsell, David S.
AU - Green, Rachel Kramer
AU - Guranovic, Vladimir
AU - Henry, Jeremy
AU - Hudson, Brian P.
AU - Khokhriakov, Igor
AU - Lawson, Catherine L.
AU - Liang, Yuhe
AU - Lowe, Robert
AU - Peisach, Ezra
AU - Persikova, Irina
AU - Piehl, Dennis W.
AU - Rose, Yana
AU - Sali, Andrej
AU - Segura, Joan
AU - Sekharan, Monica
AU - Shao, Chenghua
AU - Vallat, Brinda
AU - Voigt, Maria
AU - Webb, Ben
AU - Westbrook, John
AU - Whetstone, Shamara
AU - Young, Jasmine Y.
AU - Zalevsky, Arthur
AU - Zardecki, Christine
N1 - Publisher Copyright:
© 2023 The Author(s). Published by Oxford University Press on behalf of Nucleic Acids Research.
PY - 2023/1/6
Y1 - 2023/1/6
N2 - The Research Collaboratory for Structural Bioinformatics Protein Data Bank (RCSB PDB), founding member of the Worldwide Protein Data Bank (wwPDB), is the US data center for the open-access PDB archive. As wwPDB-designated Archive Keeper, RCSB PDB is also responsible for PDB data security. Annually, RCSB PDB serves >10 000 depositors of three-dimensional (3D) biostructures working on all permanently inhabited continents. RCSB PDB delivers data from its research-focused RCSB.org web portal to many millions of PDB data consumers based in virtually every United Nations-recognized country, territory, etc. This Database Issue contribution describes upgrades to the research-focused RCSB.org web portal that created a one-stop-shop for open access to ∼200 000 experimentally-determined PDB structures of biological macromolecules alongside >1 000 000 incorporated Computed Structure Models (CSMs) predicted using artificial intelligence/machine learning methods. RCSB.org is a 'living data resource.' Every PDB structure and CSM is integrated weekly with related functional annotations from external biodata resources, providing up-to-date information for the entire corpus of 3D biostructure data freely available from RCSB.org with no usage limitations. Within RCSB.org, PDB structures and the CSMs are clearly identified as to their provenance and reliability. Both are fully searchable, and can be analyzed and visualized using the full complement of RCSB.org web portal capabilities.
AB - The Research Collaboratory for Structural Bioinformatics Protein Data Bank (RCSB PDB), founding member of the Worldwide Protein Data Bank (wwPDB), is the US data center for the open-access PDB archive. As wwPDB-designated Archive Keeper, RCSB PDB is also responsible for PDB data security. Annually, RCSB PDB serves >10 000 depositors of three-dimensional (3D) biostructures working on all permanently inhabited continents. RCSB PDB delivers data from its research-focused RCSB.org web portal to many millions of PDB data consumers based in virtually every United Nations-recognized country, territory, etc. This Database Issue contribution describes upgrades to the research-focused RCSB.org web portal that created a one-stop-shop for open access to ∼200 000 experimentally-determined PDB structures of biological macromolecules alongside >1 000 000 incorporated Computed Structure Models (CSMs) predicted using artificial intelligence/machine learning methods. RCSB.org is a 'living data resource.' Every PDB structure and CSM is integrated weekly with related functional annotations from external biodata resources, providing up-to-date information for the entire corpus of 3D biostructure data freely available from RCSB.org with no usage limitations. Within RCSB.org, PDB structures and the CSMs are clearly identified as to their provenance and reliability. Both are fully searchable, and can be analyzed and visualized using the full complement of RCSB.org web portal capabilities.
UR - http://www.scopus.com/inward/record.url?scp=85145977694&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85145977694&partnerID=8YFLogxK
U2 - 10.1093/nar/gkac1077
DO - 10.1093/nar/gkac1077
M3 - Article
C2 - 36420884
AN - SCOPUS:85145977694
SN - 0305-1048
VL - 51
SP - D488-D508
JO - Nucleic acids research
JF - Nucleic acids research
IS - 1 D
ER -