Recent advances in the use of algal polysaccharides for skin wound healing

Suneel Kumar, Ileana Marrero-Berrios, Maciej Kabat, Francois Berthiaume

Research output: Contribution to journalReview articlepeer-review

20 Scopus citations


Background: Chronic skin wounds and pressure ulcers represent major health care problems in diabetic individuals, as well as patients who suffered a spinal cord injury. Current treatment methods are only partially effective and such wounds exhibit a high recurrence rate. Open wounds are at high risk of invasive wound infections, which can lead to amputation and further disability. An interdisciplinary approach is needed to develop new and more effective therapies. Methods: The purpose of this work is to review recent studies focusing on the use of algal polysaccharides in commercially available as well as experimental wound dressings. Studies that discuss wound dressings based on algal polysaccharides, some of which also contain growth factors and even living cells, were identified and included in this review. Results and Conclusion: Algal polysaccharides possess mechanical and physical properties, along with excellent biocompatibility and biodegradability that make them suitable for a variety of applications as wound dressings. Furthermore, algal polysaccharides have been used for a dual purpose, namely as wound covering, but also as a vehicle for drug delivery to the wound site.

Original languageEnglish (US)
Pages (from-to)1236-1248
Number of pages13
JournalCurrent Pharmaceutical Design
Issue number11
StatePublished - 2019

All Science Journal Classification (ASJC) codes

  • Pharmacology
  • Drug Discovery


  • Algal polysaccharides
  • Diabetic ulcer
  • Drug delivery
  • Pressure ulcer
  • Skin
  • Spinal cord injury
  • Wound dressing


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