Relaxin is a 6-kDa member of the relaxin family of peptide hormones, similar in structure to insulin and insulin-like growth factors. In pregnancy, relaxin circulates in the blood of all mammals, although the source and pattern of relaxin secretion are species-specific. During the cycle and in early pregnancy, relaxin actions include ovarian follicular growth and remodeling, implantation and decidualization, and myometrial quiescence. Later in pregnancy, a role for relaxin has been proposed in uterine growth, remodeling the birth canal and fetal membranes in preparation for parturition, mammary gland development, and changes in maternal vasculature.
|Original language||English (US)|
|Title of host publication||Encyclopedia of Reproduction|
|Number of pages||6|
|State||Published - Jan 1 2018|
All Science Journal Classification (ASJC) codes
- Corpus luteum
- Pubic symphysis