Relaxin

Ashley F. George, Carol A. Bagnell

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

Relaxin is a 6-kDa member of the relaxin family of peptide hormones, similar in structure to insulin and insulin-like growth factors. In pregnancy, relaxin circulates in the blood of all mammals, although the source and pattern of relaxin secretion are species-specific. During the cycle and in early pregnancy, relaxin actions include ovarian follicular growth and remodeling, implantation and decidualization, and myometrial quiescence. Later in pregnancy, a role for relaxin has been proposed in uterine growth, remodeling the birth canal and fetal membranes in preparation for parturition, mammary gland development, and changes in maternal vasculature.

Original languageEnglish (US)
Title of host publicationEncyclopedia of Reproduction
PublisherElsevier
Pages591-596
Number of pages6
ISBN (Electronic)9780128151457
DOIs
StatePublished - Jan 1 2018

All Science Journal Classification (ASJC) codes

  • Medicine(all)

Keywords

  • Cardiovascular
  • Cervix
  • Corpus luteum
  • Hormone
  • Implantation
  • Peptide
  • Placenta
  • Pregnancy
  • Pubic symphysis
  • Relaxin
  • Uterus
  • Vasodilation

Fingerprint

Dive into the research topics of 'Relaxin'. Together they form a unique fingerprint.

Cite this