Reovirus guanylyltransferase is L2 gene product lambda 2

D. R. Cleveland, H. Zarbl, S. Millward

Research output: Contribution to journalArticlepeer-review

79 Scopus citations


Reovirus guanylyltransferase, studied as a covalent enzyme-GMP intermediate, was used to guanylate appropriate acceptor molecules in vitro to produce authentic cap structures. Guanylyltransferase activity was associated with λ2, the 140-kilodalton product of the L2 gene segment of reovirus serotypes 1 and 3.

Original languageEnglish (US)
Pages (from-to)307-311
Number of pages5
JournalJournal of virology
Issue number1
StatePublished - 1986
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Microbiology
  • Immunology
  • Insect Science
  • Virology

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