Research priorities for studies linking intake of low-calorie sweeteners and potentially related health outcomes

Oliver John M. Bright, Ding Ding Wang, Marissa Shams-White, Sara N. Bleic, John Foreyt, Marion Franz, Guy Johnson, Beth Trickett Manning, Rick Mattes, Xavier Pi-Sunyer, Barbara Schneeman, James Scott Parrott, Dan Steffen, Allison Sylvetsky, Paula Ziegler, Mei Chung

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

Background: In a world of finite research funding, efforts to prioritize future research topics are increasingly necessary. Objective: The aim of this study was to identify and prioritize the direction of future research in the broad area of low-calorie sweetener (LCS) intake and potentially related health outcomes by using a novel method that incorporates evidence mapping in the Agency for Healthcare Research and Quality's Future Research Needs (FRN) process. Methods: A diverse expert stakeholder panel was convened and engaged to identify research gaps and prioritize future research needs. An independent research team hosted a number of interactive webinars and elicited feedback through surveys and individual interviews with the stakeholder panel, which included policymakers, lay audience members, health providers, a research funder, individuals with food industry experience, and researchers of several different specialties. Results: The stakeholder panel generated and ranked a list of 18 FRN questions across 5 broad research areas. Overall, stakeholder panel members unanimously agreed that the research questions that will have the largest public health impact are those that address outcomes related to body weight, appetite, and dietary intake. Although the LCSs included in this FRN project have all been Generally Recognized as Safe by the FDA or approved as food additives, the recurrent concerns and confusions with regard to the "safety" of LCSs by consumers underscore the importance of communicating the science to the general public. Conclusion: Our project provides evidence that engaging a diverse expert stakeholder panel is an effective method of translating gaps in nutrition research into prioritized areas of future research.

Original languageEnglish (US)
Article numbere000547
JournalCurrent Developments in Nutrition
Volume1
Issue number7
DOIs
StatePublished - Jul 1 2017

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Sweetening Agents
sweeteners
stakeholders
Health
Research
nutrition research
research support
food additives
Food Additives
appetite
Food Industry
Health Services Research
health services
Appetite
food industry
food intake
interviews
public health
researchers
methodology

All Science Journal Classification (ASJC) codes

  • Medicine (miscellaneous)
  • Nutrition and Dietetics
  • Food Science

Keywords

  • Artificial sweeteners
  • Future research needs
  • High-intensity sweeteners
  • Low-calorie sweeteners
  • Non-nutritive sweeteners

Cite this

Bright, O. J. M., Wang, D. D., Shams-White, M., Bleic, S. N., Foreyt, J., Franz, M., ... Chung, M. (2017). Research priorities for studies linking intake of low-calorie sweeteners and potentially related health outcomes. Current Developments in Nutrition, 1(7), [e000547]. https://doi.org/10.3945/cdn.117.000547
Bright, Oliver John M. ; Wang, Ding Ding ; Shams-White, Marissa ; Bleic, Sara N. ; Foreyt, John ; Franz, Marion ; Johnson, Guy ; Manning, Beth Trickett ; Mattes, Rick ; Pi-Sunyer, Xavier ; Schneeman, Barbara ; Parrott, James Scott ; Steffen, Dan ; Sylvetsky, Allison ; Ziegler, Paula ; Chung, Mei. / Research priorities for studies linking intake of low-calorie sweeteners and potentially related health outcomes. In: Current Developments in Nutrition. 2017 ; Vol. 1, No. 7.
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Bright, OJM, Wang, DD, Shams-White, M, Bleic, SN, Foreyt, J, Franz, M, Johnson, G, Manning, BT, Mattes, R, Pi-Sunyer, X, Schneeman, B, Parrott, JS, Steffen, D, Sylvetsky, A, Ziegler, P & Chung, M 2017, 'Research priorities for studies linking intake of low-calorie sweeteners and potentially related health outcomes', Current Developments in Nutrition, vol. 1, no. 7, e000547. https://doi.org/10.3945/cdn.117.000547

Research priorities for studies linking intake of low-calorie sweeteners and potentially related health outcomes. / Bright, Oliver John M.; Wang, Ding Ding; Shams-White, Marissa; Bleic, Sara N.; Foreyt, John; Franz, Marion; Johnson, Guy; Manning, Beth Trickett; Mattes, Rick; Pi-Sunyer, Xavier; Schneeman, Barbara; Parrott, James Scott; Steffen, Dan; Sylvetsky, Allison; Ziegler, Paula; Chung, Mei.

In: Current Developments in Nutrition, Vol. 1, No. 7, e000547, 01.07.2017.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Research priorities for studies linking intake of low-calorie sweeteners and potentially related health outcomes

AU - Bright, Oliver John M.

AU - Wang, Ding Ding

AU - Shams-White, Marissa

AU - Bleic, Sara N.

AU - Foreyt, John

AU - Franz, Marion

AU - Johnson, Guy

AU - Manning, Beth Trickett

AU - Mattes, Rick

AU - Pi-Sunyer, Xavier

AU - Schneeman, Barbara

AU - Parrott, James Scott

AU - Steffen, Dan

AU - Sylvetsky, Allison

AU - Ziegler, Paula

AU - Chung, Mei

PY - 2017/7/1

Y1 - 2017/7/1

N2 - Background: In a world of finite research funding, efforts to prioritize future research topics are increasingly necessary. Objective: The aim of this study was to identify and prioritize the direction of future research in the broad area of low-calorie sweetener (LCS) intake and potentially related health outcomes by using a novel method that incorporates evidence mapping in the Agency for Healthcare Research and Quality's Future Research Needs (FRN) process. Methods: A diverse expert stakeholder panel was convened and engaged to identify research gaps and prioritize future research needs. An independent research team hosted a number of interactive webinars and elicited feedback through surveys and individual interviews with the stakeholder panel, which included policymakers, lay audience members, health providers, a research funder, individuals with food industry experience, and researchers of several different specialties. Results: The stakeholder panel generated and ranked a list of 18 FRN questions across 5 broad research areas. Overall, stakeholder panel members unanimously agreed that the research questions that will have the largest public health impact are those that address outcomes related to body weight, appetite, and dietary intake. Although the LCSs included in this FRN project have all been Generally Recognized as Safe by the FDA or approved as food additives, the recurrent concerns and confusions with regard to the "safety" of LCSs by consumers underscore the importance of communicating the science to the general public. Conclusion: Our project provides evidence that engaging a diverse expert stakeholder panel is an effective method of translating gaps in nutrition research into prioritized areas of future research.

AB - Background: In a world of finite research funding, efforts to prioritize future research topics are increasingly necessary. Objective: The aim of this study was to identify and prioritize the direction of future research in the broad area of low-calorie sweetener (LCS) intake and potentially related health outcomes by using a novel method that incorporates evidence mapping in the Agency for Healthcare Research and Quality's Future Research Needs (FRN) process. Methods: A diverse expert stakeholder panel was convened and engaged to identify research gaps and prioritize future research needs. An independent research team hosted a number of interactive webinars and elicited feedback through surveys and individual interviews with the stakeholder panel, which included policymakers, lay audience members, health providers, a research funder, individuals with food industry experience, and researchers of several different specialties. Results: The stakeholder panel generated and ranked a list of 18 FRN questions across 5 broad research areas. Overall, stakeholder panel members unanimously agreed that the research questions that will have the largest public health impact are those that address outcomes related to body weight, appetite, and dietary intake. Although the LCSs included in this FRN project have all been Generally Recognized as Safe by the FDA or approved as food additives, the recurrent concerns and confusions with regard to the "safety" of LCSs by consumers underscore the importance of communicating the science to the general public. Conclusion: Our project provides evidence that engaging a diverse expert stakeholder panel is an effective method of translating gaps in nutrition research into prioritized areas of future research.

KW - Artificial sweeteners

KW - Future research needs

KW - High-intensity sweeteners

KW - Low-calorie sweeteners

KW - Non-nutritive sweeteners

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