Retinal cotton-wool spots: An early finding in diabetic retinopathy?

M. S. Roy, M. E. Rick, K. E. Higgins, J. C. McCulloch

Research output: Contribution to journalArticlepeer-review

23 Scopus citations

Abstract

Five insulin dependent diabetic patients are reported on who had a few small retinal cotton-wool spots or 'soft exudates' either totally isolated or associated with fewer than 10 microaneurysms. These observations suggest that cotton-wool spots may be an early finding in diabetic retinopathy. Significant biological abnormalities in these patients were high levels of glycosylated haemoglobin and mild increases in thrombin generation, indicating slight activation of the coagulation system. The possible significance of these clinical and biological findings is discussed.

Original languageEnglish (US)
Pages (from-to)772-778
Number of pages7
JournalBritish Journal of Ophthalmology
Volume70
Issue number10
DOIs
StatePublished - 1986
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Ophthalmology
  • Sensory Systems
  • Cellular and Molecular Neuroscience

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