Retraction notice: “Synthetic triterpenoids, CDDO-Imidazolide and CDDO-Ethyl amide, induce chondrogenesis” (Osteoarthritis and Cartilage (2012) 20(5) (446–450), (S1063458412000568), (10.1016/j.joca.2012.01.018))

N. Suh, S. Paul, H. J. Lee, T. Yoon, N. Shah, A. I. Son, A. H. Reddi, D. Medici, M. B. Sporn

Research output: Contribution to journalComment/debatepeer-review

Abstract

This article has been retracted: please see Elsevier Policy on Article Withdrawal (https://www.elsevier.com/about/our-business/policies/article-withdrawal). This article has been retracted at the request of the Editor-in-Chief due to serious problems with image manipulation. The Smad5 blots in Fig. 1(D) have been demonstrated to be identical with the β-actin blots from an antecedent publication in Biochemical Journal (Medici D, Potenta S, Kalluri R: Transforming growth factor-β2 promotes Snail-mediated endothelial-mesenchymal transition through convergence of Smad-dependent and Smad-independent signaling. Biochem J. 2011 Aug 1;437(3):515-20. doi: 10.1042/BJ20101500. PMID: 21585337). This has been the subject of a thorough investigation at the home institution of the author who produced the blots, and confirmed by the Editors of OAC. The co-authors of this study, Drs. Suh, Reddi, and Sporn have stated that all data for Table I were produced completely independently and they stand by the veracity of all but the offending Figure. The scientific community takes a very strong view on this matter and apologies are offered to readers of the journal that this was not detected previously.

Original languageEnglish (US)
Pages (from-to)865
Number of pages1
JournalOsteoarthritis and Cartilage
Volume28
Issue number6
DOIs
StatePublished - Jun 2020

All Science Journal Classification (ASJC) codes

  • Rheumatology
  • Biomedical Engineering
  • Orthopedics and Sports Medicine

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