Risk factors for HIV-1 and HIV-2 infection in pregnant women in dakar, senegal

Rachel C. Abbott, Anta Ndour-Sarr, Alassane Diouf, Thidiane Ndoye, Diouana Bâ, Ndèye Tall, Ngagne Mbaye, Fatou Kébé, Fadel Diadhiou, Myron E. Essex, Richard G. Marlink, Souleymane M’Boup, Karin Travers, Phyllis J. Kanki

Research output: Contribution to journalArticlepeer-review

16 Scopus citations

Abstract

This study examines the prevalence and risk factors for Human Immunodeficiency Virus type 1 (HIV-1) and type 2 (HIV-2) infection in pregnant women in Dakar, Senegal. From April 1991 to January 1993, 9,518 pregnant women were interviewed and serologically tested for antibodies to HIV-1 and HIV-2; 26 (0.3%) were HIV-1 seropositive, 44 (0.5%) were HIV-2 seropositive, two (0.02%) were dually seropositive, and 9,448 (99.3%) were seronegative. Guinea-Bissau nationality and age >25 years were associated with HIV-2 infection, whereas parity ≤2 was associated with HIV-1 infection. Among women who gave birth to live infants, shorter length of union with the partner and having been married more than once were associated with HIV-2 infection, whereas age =s25 years was associated with HIV-1 infection. Information gained by this study may help target intervention strategies for preventing maternal HIV infection and understanding biological differences between the two viruses.

Original languageEnglish (US)
Pages (from-to)711-717
Number of pages7
JournalJournal of Acquired Immune Deficiency Syndromes
Volume7
Issue number7
StatePublished - Jul 1994
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Infectious Diseases
  • Pharmacology (medical)

Keywords

  • HIV-1
  • HIV-2
  • Pregnant women
  • Risk factors
  • West Africa

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