Risk factors related to ischemic and hemorrhagic cerebrovascular disease at autopsy: The honolulu heart study

G. N. Stemmermann, T. Hayashi, J. A. Resch, C. S. Chung, D. M. Reed, G. G. Rhoads

Research output: Contribution to journalArticlepeer-review

40 Scopus citations

Abstract

This study of cerebrovascular lesions at autopsy among Hawaiian Japanese men identifies similar risks factors for cerebral infarction and hemorrhage that have been identified in a previous incidence study. Demonstrated differences were essentially the same whether subjects with these tissue changes were compared to men showing no central nervous system disease at autopsy or when they were compared with men still alive. Cerebral infarcts accompanied myocardial infarction (CHD) in 58% of autopsy cases and were associated with CHD risk factors (high serum cholesterol, hypertension, severe atherosclerosis of the coronary arteries and aorta). These associations did not persist when CHD cases were removed from the analysis, indicating there were two subsets of men with cerebral infarction. Hypertension was strongly associated with hemorrhagic disease, as were cigarette use and alcohol consumption.

Original languageEnglish (US)
Pages (from-to)23-28
Number of pages6
JournalStroke
Volume15
Issue number1
DOIs
StatePublished - 1984
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Clinical Neurology
  • Cardiology and Cardiovascular Medicine
  • Advanced and Specialized Nursing

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