RNA polymerase: Structural similarities between bacterial RNA polymerase and eukaryotic RNA polymerase II

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180 Scopus citations

Abstract

Bacterial RNA polymerase and eukaryotic RNA polymerase II exhibit striking structural similarities, including similarities in overall structure, relative positions of subunits, relative positions of functional determinants, and structures and folding topologies of subunits. These structural similarities are paralleled by similarities in mechanisms of interaction with DNA.

Original languageEnglish (US)
Pages (from-to)687-698
Number of pages12
JournalJournal of molecular biology
Volume304
Issue number5
DOIs
StatePublished - Dec 15 2000

All Science Journal Classification (ASJC) codes

  • Structural Biology
  • Molecular Biology

Keywords

  • Elongation complex
  • Open complex
  • RNA polymerase
  • RNA polymerase II
  • Transcription

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