Role of bone morphogenetic proteins in transitional cell carcinoma cells

Isaac Yi Kim, Seong Jin Kim

    Research output: Contribution to journalArticlepeer-review

    10 Scopus citations

    Abstract

    Bone morphogenetic proteins (BMPs) are pleiotropic growth factors that signal through an interaction with the membrane receptors-type-IA, -IB, and -II (BMP-RIA, -RIB, and -RII, respectively). Although the prototypical members of this group of growth factors were isolated as osteoinductive factors, recently accumulated data have suggested that these factors regulate malignant cells. Herein, we review the data concerning BMPs in transitional cell carcinoma cells.

    Original languageEnglish (US)
    Pages (from-to)118-123
    Number of pages6
    JournalCancer Letters
    Volume241
    Issue number1
    DOIs
    StatePublished - Sep 8 2006

    All Science Journal Classification (ASJC) codes

    • Oncology
    • Cancer Research

    Keywords

    • BMP receptor
    • Bladder TCC cell line
    • Bone morphogenetic proteins (BMPs)
    • Transitional cell carcinoma (TCC)

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