Role of bone morphogenetic proteins in transitional cell carcinoma cells

Isaac Yi Kim, Seong Jin Kim

Research output: Contribution to journalArticle

10 Scopus citations

Abstract

Bone morphogenetic proteins (BMPs) are pleiotropic growth factors that signal through an interaction with the membrane receptors-type-IA, -IB, and -II (BMP-RIA, -RIB, and -RII, respectively). Although the prototypical members of this group of growth factors were isolated as osteoinductive factors, recently accumulated data have suggested that these factors regulate malignant cells. Herein, we review the data concerning BMPs in transitional cell carcinoma cells.

Original languageEnglish (US)
Pages (from-to)118-123
Number of pages6
JournalCancer Letters
Volume241
Issue number1
DOIs
StatePublished - Sep 8 2006

All Science Journal Classification (ASJC) codes

  • Oncology
  • Cancer Research

Keywords

  • BMP receptor
  • Bladder TCC cell line
  • Bone morphogenetic proteins (BMPs)
  • Transitional cell carcinoma (TCC)

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