Schizophrenia and genetics: new insights.

Anne S. Bassett, Eva W. Chow, Rosanna Weksberg, Linda Brzustowicz

Research output: Contribution to journalReview article

17 Scopus citations


There is consistent evidence that the principal etiology of schizophrenia involves predisposing genetic factors. Recent years have seen several new insights in the genetics of schizophrenia. Several chromosomal regions show significant evidence that they contain schizophrenia susceptibility genes. A clinically relevant genetic subtype of schizophrenia (22q deletion syndrome) has been identified. There is new evidence that spontaneous mutations may play a role. There are new recommendations for genetic counseling. The progress to date suggests that understanding of a neurodevelopmental pathway from genetic susceptibility to schizophrenia will soon be fundamentally altered by molecular genetic advances in this complex disease.

Original languageEnglish (US)
Pages (from-to)307-314
Number of pages8
JournalCurrent psychiatry reports
Issue number4
StatePublished - Aug 2002


All Science Journal Classification (ASJC) codes

  • Psychiatry and Mental health

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