Screening for unusual matched segments in multiple protein sequences

Joseph I. Naus, Ke Ning Sheng

Research output: Contribution to journalArticle

4 Scopus citations

Abstract

Given a sequence of i.i.d. integer valued random variables, we derive the distribution of the minimum sum of any W consecutive variables. We apply these results to evaluate the unusualness of matches (perfect or almost perfect) in multiply aligned sequences, and matches in all possible alignments of sequences.

Original languageEnglish (US)
Pages (from-to)937-952
Number of pages16
JournalCommunications in Statistics Part B: Simulation and Computation
Volume25
Issue number4
DOIs
StatePublished - Jan 1 1996

All Science Journal Classification (ASJC) codes

  • Statistics and Probability
  • Modeling and Simulation

Keywords

  • Alignment
  • Mismatching
  • Scan statistics

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