Sequence-related changes in sensory-evoked potentials in the dentate gyrus: A mechanism for item-specific short-term information storage in the hippocampus

Sam A. Deadwyler, Mark O. West, Edward P. Christian, Robert E. Hampson, Thomas C. Foster

Research output: Contribution to journalArticlepeer-review

43 Scopus citations

Abstract

Sensory-evoked potentials were recorded from the dentate gyrus of the rat hippocampus during performance of a differential auditory discrimination task. The short latency (20 ms) component (N1) of the sensory-evoked potential showed systematic amplitude fluctuations dependent upon the sequence of positive and negative trials preceding the presentation of a given trial and did not depend on the associated reward values of the individual tone stimuli which evoked the potential. The amplitude fluctuations could be accurately depicted by a model which retained the sequence for the five preceding trials in a "buffer" with exponentially decaying influence as a function of time of trial occurrence within the sequence. The results provide evidence that the hippocampus encodes accurate short-lasting representations of sensory events which can provide the basis for storage of information pertaining to past experiences.

Original languageEnglish (US)
Pages (from-to)201-212
Number of pages12
JournalBehavioral and Neural Biology
Volume44
Issue number2
DOIs
StatePublished - Sep 1985
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Physiology

Fingerprint

Dive into the research topics of 'Sequence-related changes in sensory-evoked potentials in the dentate gyrus: A mechanism for item-specific short-term information storage in the hippocampus'. Together they form a unique fingerprint.

Cite this