Serologic Reactivity in Consecutive Patients Admitted to a General Hospital: A Comparison of the FTA-ABS, VDRL, and Automated Reagin Tests

Paul Cohen, Genevieve Stout, Norman Ende

Research output: Contribution to journalArticlepeer-review

21 Scopus citations

Abstract

Treponemal (fluorescent treponemal antibody-absorption [FTA-ABS]) and nontreponemal (Venereal Disease Research Laboratory [VDRL] and automated reagin) tests were performed on patients consecutively admitted to a general hospital. The FTA-ABS test was reactive in 16.8% of the patients compared with a 9.5% reactivity rate for the VDRL test. A history of treated or untreated syphilis was obtained in 73 of 78 patients with a reactive FTA-ABS test; in the 5 remaining patients, the diagnosis of syphilis could not definitely be established. An additional 40 (8.6%) patients demonstrated borderline reactivity in the FTA-ABS test. Of these, eight were found to have had syphilis. In the present study, the FTA-ABS test was reactive more often than either the VDRL or the automated reagin tests; however, both the nontreponemal and treponemal tests were reactive in three patients who had previously undetected, untreated syphilis.

Original languageEnglish (US)
Pages (from-to)364-367
Number of pages4
JournalArchives of Internal Medicine
Volume124
Issue number3
DOIs
StatePublished - Sep 1969
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Internal Medicine

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