Serum Triiodothyronine Concentrations in Riboflavin-Deficient, Diabetic and Normal Mice

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The riboflavin nutritional status was assessed by activity coefficient (AC) of glutathione reductase in erythrocyte hemolysates of normal Swiss albino (SA) and genetically diabetic (KK) mice aged 8-9 months. AC values greater than 1.3 were considered as evidence of riboflavin deficiency. Based upon AC values, both SA and KK mice were divided into normal and riboflavin-deficient groups. In some young SA mice, riboflavin deficiency was produced by feeding of a riboflavin-deficient diet. In both normal and riboflavin-deficient mice, the serum L-triiodothyronine (T3) concentrations were determined by radioimmunoassay. The results indicate that the T3 concentration is not affected either in riboflavin deficiency or in genetic diabetes.

Original languageEnglish (US)
Pages (from-to)690-693
Number of pages4
JournalProceedings of the Society for Experimental Biology and Medicine
Issue number4
StatePublished - Jan 1 1978
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Biochemistry, Genetics and Molecular Biology(all)

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