Sharing calcium opens new avenues of signalling

A. P. Thomas

doi:10.1038/35017143

Sharing calcium opens new avenues of signalling

A. P. Thomas

Research output: Contribution to journal › Short survey › peer-review

16 Scopus citations

Abstract

A consequence of intracellular calcium signalling is that calcium released into the cytosol is extruded from the cell. New research shows that when the interstitial space is constricted, calcium extruded from one cell may increase levels of calcium in the surrounding medium sufficiently to activate calcium-sensing receptors on the surfaces of adjacent cells. Thus, the calcium that serves as an intracellular signal can also serve as an extracellular signal to recruit neighbouring cells.

Original language	English (US)
Pages (from-to)	E126-E128
Journal	Nature Cell Biology
Volume	2
Issue number	7
DOIs	https://doi.org/10.1038/35017143
State	Published - 2000

All Science Journal Classification (ASJC) codes

Cell Biology

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10.1038/35017143

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title = "Sharing calcium opens new avenues of signalling",

abstract = "A consequence of intracellular calcium signalling is that calcium released into the cytosol is extruded from the cell. New research shows that when the interstitial space is constricted, calcium extruded from one cell may increase levels of calcium in the surrounding medium sufficiently to activate calcium-sensing receptors on the surfaces of adjacent cells. Thus, the calcium that serves as an intracellular signal can also serve as an extracellular signal to recruit neighbouring cells.",

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AB - A consequence of intracellular calcium signalling is that calcium released into the cytosol is extruded from the cell. New research shows that when the interstitial space is constricted, calcium extruded from one cell may increase levels of calcium in the surrounding medium sufficiently to activate calcium-sensing receptors on the surfaces of adjacent cells. Thus, the calcium that serves as an intracellular signal can also serve as an extracellular signal to recruit neighbouring cells.

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Sharing calcium opens new avenues of signalling

Abstract

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