Simulated parametric studies in optical imaging of tumors through temporal log-slope difference mapping

Zhixiong Guo, Siew Kan Wan

Research output: Contribution to journalArticlepeer-review

4 Scopus citations

Abstract

Numerical studies are conducted to evaluate the noninvasive imaging method of temporal log-slope difference mapping (TLSDM). Emphasis is placed on the parametric examination of tumor's size, enhanced absorption contrast ratio, and embedment depth on the imaging quality and accuracy. It is found that the imaging quality and accuracy are predominantly determined by the tumor size and its embedment depth. The TLSDM method can detect a small tumor of 10 mm in size when the tumor is embedded at a shallow depth down to 10 mm. With decreasing tumor size and/or increasing embedment depth, both image quality and accuracy worsen. The imaging method requires the enhanced absorption contrast ratio be 20:1 or above.

Original languageEnglish (US)
Pages (from-to)1142-1148
Number of pages7
JournalMedical Engineering and Physics
Volume29
Issue number10
DOIs
StatePublished - Dec 2007

All Science Journal Classification (ASJC) codes

  • Biophysics
  • Biomedical Engineering

Keywords

  • Absorption contrast
  • Optical imaging
  • Temporal log-slope
  • Tumor detection

Fingerprint

Dive into the research topics of 'Simulated parametric studies in optical imaging of tumors through temporal log-slope difference mapping'. Together they form a unique fingerprint.

Cite this