Abstract
Mice were infected with 250 larvae of Heligmosomoides polygyrus. Seven days after infection virgin adult worms were collected and transplanted into different regions of the intestine of previously uninfected mice. In all cases the adult worms (mixed male and female, male or female) migrated anteriorly to the duodenum. Surgical alteration of the intestine involved exclusion or relocation of gastric, biliary and pancreatic secretions. Relocation of the entry of gastric secretions into the small intestine resulted in a significant entry of the gastric juices. Alteration of biliary and pancreatic secretions did not result in a change in worm distribution. The results support the hypothesis that worm site selection is determined through cues of host origin; in the case of adult H. polygyrus the cues to site selection appear to be part of the gastric secretion.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 355-358 |
| Number of pages | 4 |
| Journal | International Journal for Parasitology |
| Volume | 13 |
| Issue number | 4 |
| DOIs | |
| State | Published - Aug 1983 |
| Externally published | Yes |
All Science Journal Classification (ASJC) codes
- Parasitology
- Infectious Diseases
Keywords
- Heligmosomoides polygyrus
- adult worms
- behavioral cues
- gastrointestinal tract
- site selection
- surgery