Abstract
This study compared transcutaneous carbon dioxide partial pressure (PtcCO 2 ) and end-tidal carbon dioxide partial pressure (PetCO 2 ) monitoring during sleep for patients with neuromuscular disease. Design This is a retrospective study of patients whose PtcCO 2 and PetCO 2 were monitored before they began using noninvasive mechanical ventilation. The outcomes were divided into four groupings: group 1, both PtcCO 2 and PetCO 2 are greater than or equal to 49 mm Hg; group 2, PtcCO 2 is greater than or equal to 49 mm Hg but PetCO 2 is less than 49 mm Hg; group 3, PtcCO 2 is less than 49 mm Hg but PetCO 2 is greater than or equal to 49 mm Hg; and group 4, both PtcCO 2 and PetCO 2 are less than 49 mm Hg. Results A total of 39 subjects (mean [SD] age, 27.7 [19.3] yrs) were enrolled. PtcCO 2 values were significantly higher than PetCO 2 values (P < 0.001). The intraclass correlation coefficient between maximal and mean values of PtcCO 2 and PetCO 2 was 0.612 and 0.718, respectively. Bias and limits of agreement between PtcCO 2 and PetCO 2 were-7.5 mm Hg and-21.3 to 6.3 mm Hg for maximal values and-4.8 mm Hg and-14.8 to 5.3 mm Hg for mean values. Group 2 included 19 (48.7%) and group 3 included 3 (7.6%) patients who showed discrepancy of hypercapnia between two methods. Conclusions Maximum PtcCO 2 was significantly greater than maximum PetCO 2 for both groups and, therefore, tends to be higher than PetCO 2 in this population. This should be taken into consideration when assessing patients for sleep hypoventilation.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 91-95 |
| Number of pages | 5 |
| Journal | American Journal of Physical Medicine and Rehabilitation |
| Volume | 95 |
| Issue number | 2 |
| DOIs | |
| State | Published - Feb 1 2016 |
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All Science Journal Classification (ASJC) codes
- Physical Therapy, Sports Therapy and Rehabilitation
- Rehabilitation
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Sleep Transcutaneous vs. End-Tidal CO 2 Monitoring for Patients with Neuromuscular Disease . / Won, Yu Hui; Choi, Won Ah; Lee, Jang Woo; Bach, John; Park, Jinyoung; Kang, Seong Woong.
In: American Journal of Physical Medicine and Rehabilitation, Vol. 95, No. 2, 01.02.2016, p. 91-95.Research output: Contribution to journal › Article
TY - JOUR
T1 - Sleep Transcutaneous vs. End-Tidal CO 2 Monitoring for Patients with Neuromuscular Disease
AU - Won, Yu Hui
AU - Choi, Won Ah
AU - Lee, Jang Woo
AU - Bach, John
AU - Park, Jinyoung
AU - Kang, Seong Woong
PY - 2016/2/1
Y1 - 2016/2/1
N2 - This study compared transcutaneous carbon dioxide partial pressure (PtcCO 2 ) and end-tidal carbon dioxide partial pressure (PetCO 2 ) monitoring during sleep for patients with neuromuscular disease. Design This is a retrospective study of patients whose PtcCO 2 and PetCO 2 were monitored before they began using noninvasive mechanical ventilation. The outcomes were divided into four groupings: group 1, both PtcCO 2 and PetCO 2 are greater than or equal to 49 mm Hg; group 2, PtcCO 2 is greater than or equal to 49 mm Hg but PetCO 2 is less than 49 mm Hg; group 3, PtcCO 2 is less than 49 mm Hg but PetCO 2 is greater than or equal to 49 mm Hg; and group 4, both PtcCO 2 and PetCO 2 are less than 49 mm Hg. Results A total of 39 subjects (mean [SD] age, 27.7 [19.3] yrs) were enrolled. PtcCO 2 values were significantly higher than PetCO 2 values (P < 0.001). The intraclass correlation coefficient between maximal and mean values of PtcCO 2 and PetCO 2 was 0.612 and 0.718, respectively. Bias and limits of agreement between PtcCO 2 and PetCO 2 were-7.5 mm Hg and-21.3 to 6.3 mm Hg for maximal values and-4.8 mm Hg and-14.8 to 5.3 mm Hg for mean values. Group 2 included 19 (48.7%) and group 3 included 3 (7.6%) patients who showed discrepancy of hypercapnia between two methods. Conclusions Maximum PtcCO 2 was significantly greater than maximum PetCO 2 for both groups and, therefore, tends to be higher than PetCO 2 in this population. This should be taken into consideration when assessing patients for sleep hypoventilation.
AB - This study compared transcutaneous carbon dioxide partial pressure (PtcCO 2 ) and end-tidal carbon dioxide partial pressure (PetCO 2 ) monitoring during sleep for patients with neuromuscular disease. Design This is a retrospective study of patients whose PtcCO 2 and PetCO 2 were monitored before they began using noninvasive mechanical ventilation. The outcomes were divided into four groupings: group 1, both PtcCO 2 and PetCO 2 are greater than or equal to 49 mm Hg; group 2, PtcCO 2 is greater than or equal to 49 mm Hg but PetCO 2 is less than 49 mm Hg; group 3, PtcCO 2 is less than 49 mm Hg but PetCO 2 is greater than or equal to 49 mm Hg; and group 4, both PtcCO 2 and PetCO 2 are less than 49 mm Hg. Results A total of 39 subjects (mean [SD] age, 27.7 [19.3] yrs) were enrolled. PtcCO 2 values were significantly higher than PetCO 2 values (P < 0.001). The intraclass correlation coefficient between maximal and mean values of PtcCO 2 and PetCO 2 was 0.612 and 0.718, respectively. Bias and limits of agreement between PtcCO 2 and PetCO 2 were-7.5 mm Hg and-21.3 to 6.3 mm Hg for maximal values and-4.8 mm Hg and-14.8 to 5.3 mm Hg for mean values. Group 2 included 19 (48.7%) and group 3 included 3 (7.6%) patients who showed discrepancy of hypercapnia between two methods. Conclusions Maximum PtcCO 2 was significantly greater than maximum PetCO 2 for both groups and, therefore, tends to be higher than PetCO 2 in this population. This should be taken into consideration when assessing patients for sleep hypoventilation.
UR - http://www.scopus.com/inward/record.url?scp=84954415608&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84954415608&partnerID=8YFLogxK
U2 - 10.1097/PHM.0000000000000345
DO - 10.1097/PHM.0000000000000345
M3 - Article
C2 - 26135371
AN - SCOPUS:84954415608
VL - 95
SP - 91
EP - 95
JO - American Journal of Physical Medicine and Rehabilitation
JF - American Journal of Physical Medicine and Rehabilitation
SN - 0894-9115
IS - 2
ER -