Social Impact of Hepatic Encephalopathy

Mishal Reja, Lauren Pioppo Phelan, Frank Senatore, Vinod K. Rustgi

Research output: Contribution to journalReview articlepeer-review

1 Scopus citations


Hepatic encephalopathy (HE) is a multifaceted disorder, with effects stretching far beyond office visits and hospitalizations. Patients with HE suffer from varying degrees of altered consciousness, intellectual disability, and personality changes. A large social impact exists for patients with HE. Quality of life and activities of daily living, such as work capacity, driving ability, and sleep quality, have been shown to be affected. Additionally, caregiver and financial burdens are highly prevalent. Multiple tools exist to assess quality of life, including the CLD-Q questionnaire. Common treatments for HE, including rifaximin and lactulose, have been shown to improve overall quality of life.

Original languageEnglish (US)
Pages (from-to)291-301
Number of pages11
JournalClinics in Liver Disease
Issue number2
StatePublished - May 2020

All Science Journal Classification (ASJC) codes

  • Hepatology


  • Caregiver
  • Driving
  • Finance
  • Quality of life
  • Sleep
  • Social impact


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