Spinning a magical web: The combination of fast magic-angle spinning, isotopic dilution, and high magnetic field yields particularly well-resolved solid-state 1H NMR spectra, which are efficiently utilized to solve protein structure. New techniques are demonstrated, requiring only three days of data collection, to assign the proton signals and solve a high-resolution structure of microcrystalline GB1. (Graph Presented).
All Science Journal Classification (ASJC) codes
- Indirect proton detection
- Magic-angle spinning
- NMR spectroscopy
- Protein structures