Somatostatin neurons in the rodent hippocampus: An in vitro and in vivo immunocytochemical study

Susan C. Feldman, Cheryl F. Dreyfus, Eric S. Lichtenstein

Research output: Contribution to journalArticlepeer-review

39 Scopus citations

Abstract

The origin and distribution of immunoreactive-like somatostatin (ISRIF) in the rodent hippocampus was determined by light microscopic immunocytochemistry. ISRIF neurons were demonstrable in long-term explants of fetal mouse hippocampus, demonstrating that a population of SRIF neurons are intrinsic to the hippocampus. In the adult rat, mouse and guinea pig ISRIF was present in several types of neurons - including pyramidal, basket and multipolar neurons - and in all hippocampal regions except for the granule cells of the dentate gyrus. These results suggest that the same molecule is found in neurons which may subserve different functions.

Original languageEnglish (US)
Pages (from-to)29-34
Number of pages6
JournalNeuroscience Letters
Volume33
Issue number1
DOIs
StatePublished - Nov 16 1982
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • General Neuroscience

Keywords

  • hippocampus
  • immunocytochemistry
  • rodent
  • somatostatin
  • tissu culture

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