The origin and distribution of immunoreactive-like somatostatin (ISRIF) in the rodent hippocampus was determined by light microscopic immunocytochemistry. ISRIF neurons were demonstrable in long-term explants of fetal mouse hippocampus, demonstrating that a population of SRIF neurons are intrinsic to the hippocampus. In the adult rat, mouse and guinea pig ISRIF was present in several types of neurons - including pyramidal, basket and multipolar neurons - and in all hippocampal regions except for the granule cells of the dentate gyrus. These results suggest that the same molecule is found in neurons which may subserve different functions.
All Science Journal Classification (ASJC) codes
- tissu culture