Spontaneous regression of Friend virus induced leukemia: Coinfection with regressing and conventional strains of virus

Philip Furmanski, James Baldwin, Rodney Clymer, Marvin A. Rich

Research output: Contribution to journalArticlepeer-review

7 Scopus citations

Abstract

Mixtures of Friend virus (CFV) and the regressing strain of Friend virus (RFV) induce leukemia which regresses. The dominance of the regressing phenotype is solely a function of a threshold dose of RFV. The minimum amount of RFV which induced regression of CFV leukemia is below the titer for induction of Friend disease, but does correlate with the titer of lymphocytic leukemia (helper) activity in these stocks.

Original languageEnglish (US)
Pages (from-to)72-73
Number of pages2
JournalScience
Volume187
Issue number4171
DOIs
StatePublished - 1975
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • General

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