Statistical genetic terminology

Robert C. Elston, Jaya Satagopan, Shuying Sun

Research output: Chapter in Book/Report/Conference proceedingChapter

1 Scopus citations

Abstract

Common terms used in statistical genetics with multiple meanings are explained and the terminology used in subsequent chapters is defined. Statistical human genetics has existed as a discipline for over a century, and during that time the meanings of many of the terms used have evolved, largely driven by molecular discoveries, to the point that molecular geneticists, statistical geneticists, and statisticians often have difficulty understanding each other. It is therefore imperative, now that so much of molecular genetics is becoming an in silico and statistical science, that we have a well-defined, common terminology.

Original languageEnglish (US)
Title of host publicationMethods in Molecular Biology
PublisherHumana Press Inc.
Pages1-9
Number of pages9
DOIs
StatePublished - 2017
Externally publishedYes

Publication series

NameMethods in Molecular Biology
Volume1666
ISSN (Print)1064-3745

All Science Journal Classification (ASJC) codes

  • Molecular Biology
  • Genetics

Keywords

  • Additive
  • Allele
  • Allelic association
  • Codominant
  • Complex trait
  • Diallelic
  • Dominant
  • Epistasis
  • Gametic phase disequilibrium
  • Gene
  • Genotype
  • Haplotype
  • Identity by descent
  • Identity in state
  • Interaction
  • Kinship coefficient
  • Linkage disequilibrium
  • Locus
  • Logit
  • Mixed model
  • Monoallelic
  • Monogenic
  • Monomorphic
  • Multiallelic
  • Multifactorial
  • Multilocus genotype
  • Mutation
  • Penetrance
  • Phase
  • Phenoset
  • Phenotype
  • Pleiotropy
  • Polyallelic
  • Polygenic
  • Polymorphism
  • Probit
  • Quantitative trait locus
  • Recessive
  • Scale of measurement
  • Site
  • Transformation
  • Transition probability
  • Transmission probability

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