Structural and functional constraints in the display of peptides on filamentous phage capsids

Gianni Cesareni, Olga Minenkova, Luciana Dente, Gioacchino Iannolo, Adriana Zucconi, Manuela Helmer Citterich, Alessandra Lanfrancotti, Luisa Castagnoli, Costantino Vetriani

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

Recently a series of different approaches grouped under the general term of “in vitro evolution�? have raised considerable interest (Kauffman, 1993; Bartel and Szostak, 1993; Tuerk and Gold, 1990; Smith and Scott, 1993; Lowman et al., 1991; Stemmer, 1994). In synthesis, the idea is to mimic the natural selection process, in the test tube, in order to either select molecules with new properties or acquire information about the possible routes explored by nature in evolving contemporary structures, functions and organisms.

Original languageEnglish (US)
Title of host publicationCombinatorial Libraries
Subtitle of host publicationSynthesis, Screening and Application Potential
Publisherde Gruyter
Pages113-126
Number of pages14
ISBN (Electronic)9783110808902
ISBN (Print)311014395X, 9783110143959
DOIs
Publication statusPublished - Jan 1 2013
Externally publishedYes

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All Science Journal Classification (ASJC) codes

  • Biochemistry, Genetics and Molecular Biology(all)

Cite this

Cesareni, G., Minenkova, O., Dente, L., Iannolo, G., Zucconi, A., Citterich, M. H., ... Vetriani, C. (2013). Structural and functional constraints in the display of peptides on filamentous phage capsids. In Combinatorial Libraries: Synthesis, Screening and Application Potential (pp. 113-126). de Gruyter. https://doi.org/10.1515/9783110808902.113