Structure of HIV-1 reverse transcriptase bound to a novel 38-mer hairpin template-primer DNA aptamer

Keyphrases

• 2′-O-methylation 16%
• 3' End 16%
• Active Sites 16%
• Anti-HIV 16%
• Antibody Fab Fragment 16%
• Aptamer 33%
• Aptamer Design 16%
• Deoxythymidine 16%
• DNA Aptamer 100%
• DNA Complex 16%
• DNA Interstrand Crosslinks 16%
• Duplex 33%
• Fragment Screening 16%
• Hairpin 100%
• Hairpin DNA 16%
• Hairpin Loop 16%
• High Affinity 33%
• HIV Inhibitors 16%
• HIV-1 Reverse Transcriptase 100%
• Modified DNA 16%
• Nucleic Acid Structure 16%
• Overhang 16%
• Polymerase 16%
• Reverse Transcriptase 100%
• Template-primer 100%
• Ultra-high 16%
• X-ray Structure Determination 16%

Biochemistry, Genetics and Molecular Biology

• Active Site 11%
• Aptamer 100%
• Crosslinking of DNA 11%
• DNA Hairpin 11%
• DNA Template 100%
• Human Immunodeficiency Virus 11%
• Nucleic Acid Structure 11%
• Nucleotide 11%
• Polymerase 11%
• Reverse Transcriptase 100%
• X-Ray Diffraction 11%