The unusual behavior of the ethyl ester of 5-amino-3-methylisoxazole-4- carboxylic acid (1) during deamination is described. Possible explanations for the anomalies of the diazotization reaction are proposed. Deamination methods leading to ethyl ester of 3-methylisoxazole-4-carboxylic acid (5) are presented. 5 will serve as a lead compound for a new series of immunomodulatory agents.
|Original language||English (US)|
|Number of pages||7|
|Journal||Polish Journal of Chemistry|
|Publication status||Published - May 1 2009|
All Science Journal Classification (ASJC) codes
- Hydrogen bonding
- Immunological activity