@article{591caca9be92456382fab1c20511f604,
title = "Studies with the neurotoxicant 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) and several of its analogs",
abstract = "The nigrostriatal dopaminergic neurotoxicity of MPTP was prevented in mice in a dose-dependent manner by the monoamine oxidase-B (MAO-B) inhibitor deprenyl. This finding, combined with other observations, points out the important role of MAO-B in the bioactivation of MPTP. In the present study, some comparisons between MPTP and several of its structural analogs will be presented.",
keywords = "Dopamine, MPTP, Monoamine oxidase, Parkinsonism",
author = "Heikkila, {Richard E.} and Youngster, {Stephen K.} and Panek, {Diana U.} and Andrew Giovanni and Sonsalla, {Patricia K.}",
note = "Funding Information: We would like to thank all of our colleagues who have worked with us on various aspects of these studies. Supported in part by grants from the United States Public Health Service, the Smokeless Tobacco Research Council, the American Parkinson Disease Association, and the United Parkinson Foundation.",
year = "1988",
month = may,
doi = "10.1016/0300-483X(88)90035-2",
language = "English (US)",
volume = "49",
pages = "493--501",
journal = "Toxicology",
issn = "0300-483X",
publisher = "Elsevier Ireland Ltd",
number = "2-3",
}