Studying the single life of eukaryotic microbes: Single-cell genomics of marine plankton

Debashish Bhattacharya, Rajat S. Roy, Dana C. Price, Alexander Schliep

Research output: Contribution to journalArticlepeer-review

1 Scopus citations


The oceans are full of innumerable numbers of single cells living in microenvironments. Understanding who they are, what they eat and what infects them can inform us about the true diversity of plankton, their biotic interactions and how they may respond to a changing environment. Analysing to significant depth the genomes and 'gut' (i.e. the food vacuole and other contents) of individual wild-caught cells would have been thought impossible only a few years ago. However, the rapidly expanding field of single-cell genomics, powered by modern cell-sorting procedures, high-throughput DNA sequencing and bioinformatics methods holds the promise to revolutionize understanding of the biodiversity and ecology of eukaryotic microbes and their places in the tree of life.

Original languageEnglish (US)
Pages (from-to)16-22
Number of pages7
Issue number1
StatePublished - Feb 2014

All Science Journal Classification (ASJC) codes

  • Biochemistry, Genetics and Molecular Biology(all)


  • Eukaryote
  • Metagenome
  • Picobiliphyte
  • Sanger dideoxy sequencing


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