Surfing on Calcium Waves

Janet Alder, James Q. Zheng

Research output: Contribution to journalShort surveypeer-review

1 Scopus citations

Abstract

A key question in brain development is how migration of neuronal precursors is guided to establish the ordered laminar layers. In the April 20, 2007 issue of Cell, Guan et al. show that the leading process of migrating cerebellar granule neurons senses repulsive Slit molecules by generating a Ca2+ wave that propagates to the soma to cause reversal of cell polarity and migration.

Original languageEnglish (US)
Pages (from-to)502-505
Number of pages4
JournalNeuron
Volume54
Issue number4
DOIs
StatePublished - May 24 2007

All Science Journal Classification (ASJC) codes

  • Neuroscience(all)

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