The title compound (9b) was prepared in five steps (48% overall yield) from ethyl 2,3,6-trideoxy-α-D-erythro-hex-2-enopyranoside (4b) as a 1:2.3 mixture of a- and /3-anomers. The key step was the iodocyclization reaction of unsaturated carbonimidothioate derivative 5. An improved procedure for the synthesis of 4b is also described.
All Science Journal Classification (ASJC) codes
- Organic Chemistry