Synthesis of (+)-Tetrahydropseudodistomin

Spencer Knapp, Jeffrey J. Hale

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Abstract

The stereocontrolled synthesis of (+)-tetra-hydropseudodistomin (3) from d-serine features the use of the dibenzyltriazone group for amino protection and establishes the absolute stereochemistry of the naturally occurring calmodulin antagonists pseudodistomin A and B (1 and 2b, respectively).

Original languageEnglish (US)
Pages (from-to)2650-2651
Number of pages2
JournalJournal of Organic Chemistry
Volume58
Issue number10
DOIs
Publication statusPublished - Jan 1 1993

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All Science Journal Classification (ASJC) codes

  • Organic Chemistry

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