Synthesis of the Ezomycin Octosyl Nucleoside

Spencer Knapp; Wen Chung Shieh; Carlos Jaramillo; Richard V. Trilles; Santosh R. Nandan

doi:10.1021/jo00084a005

Synthesis of the Ezomycin Octosyl Nucleoside

Spencer Knapp, Wen Chung Shieh, Carlos Jaramillo, Richard V. Trilles, Santosh R. Nandan

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38 Scopus citations

Abstract

Efficient chain extension of β-ᴅ-galactopyranosyl cyanide, cyclization to a bicyclic octose, and then attachment of cytosine affords the ezomycin octosyl nucleoside 17 in a form suitable for elaboration to the ezomycins (e.g., 1).

Original language	English (US)
Pages (from-to)	946-948
Number of pages	3
Journal	Journal of Organic Chemistry
Volume	59
Issue number	5
DOIs	https://doi.org/10.1021/jo00084a005
State	Published - Mar 1 1994

All Science Journal Classification (ASJC) codes

Organic Chemistry

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10.1021/jo00084a005

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@article{f23e9105cb8d4357b8ce6cae4c36ca0a,

title = "Synthesis of the Ezomycin Octosyl Nucleoside",

abstract = "Efficient chain extension of β-ᴅ-galactopyranosyl cyanide, cyclization to a bicyclic octose, and then attachment of cytosine affords the ezomycin octosyl nucleoside 17 in a form suitable for elaboration to the ezomycins (e.g., 1).",

author = "Spencer Knapp and Shieh, {Wen Chung} and Carlos Jaramillo and Trilles, {Richard V.} and Nandan, {Santosh R.}",

year = "1994",

month = mar,

day = "1",

doi = "10.1021/jo00084a005",

language = "English (US)",

volume = "59",

pages = "946--948",

journal = "Journal of Organic Chemistry",

issn = "0022-3263",

publisher = "American Chemical Society",

number = "5",

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T1 - Synthesis of the Ezomycin Octosyl Nucleoside

AU - Knapp, Spencer

AU - Shieh, Wen Chung

AU - Jaramillo, Carlos

AU - Trilles, Richard V.

AU - Nandan, Santosh R.

PY - 1994/3/1

Y1 - 1994/3/1

N2 - Efficient chain extension of β-ᴅ-galactopyranosyl cyanide, cyclization to a bicyclic octose, and then attachment of cytosine affords the ezomycin octosyl nucleoside 17 in a form suitable for elaboration to the ezomycins (e.g., 1).

AB - Efficient chain extension of β-ᴅ-galactopyranosyl cyanide, cyclization to a bicyclic octose, and then attachment of cytosine affords the ezomycin octosyl nucleoside 17 in a form suitable for elaboration to the ezomycins (e.g., 1).

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U2 - 10.1021/jo00084a005

DO - 10.1021/jo00084a005

M3 - Article

AN - SCOPUS:0028197344

SN - 0022-3263

VL - 59

SP - 946

EP - 948

JO - Journal of Organic Chemistry

JF - Journal of Organic Chemistry

IS - 5

ER -

Synthesis of the Ezomycin Octosyl Nucleoside

Abstract

All Science Journal Classification (ASJC) codes

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