Synthesis of Versicolorin A by a Mutant Strain of Aspergillus Parasiticus Deficient in Aflatoxin Production

Louise S. Lee, Joan Bennett, Alva F. Cucullu, James B. Stanley

Research output: Contribution to journalArticle

50 Citations (Scopus)

Abstract

A mutant strain of Aspergillus parasiticus lost its aflatoxin producing ability but produced four yellow pigments. The major one represented 0.13% of the mycelial mass and was identified as versicolorin A by comparison of its physical and chemical properties with those reported for an authentic compound. A trihydroxyanthraquinone, versicolorin A contains the unique difurano group present in aflatoxins and has been proposed as an intermediate in the biosynthesis of these compounds. The isolation and identification of the pigment from mutant A. parasiticus corroborate this theory.

Original languageEnglish (US)
Pages (from-to)1132-1134
Number of pages3
JournalJournal of Agricultural and Food Chemistry
Volume23
Issue number6
DOIs
StatePublished - Nov 1 1975
Externally publishedYes

Fingerprint

Aspergillus parasiticus
Aflatoxins
Aspergillus
Pigments
aflatoxins
pigments
mutants
synthesis
Biosynthesis
Chemical properties
physical properties
physicochemical properties
Physical properties
biosynthesis
versicolorin A

All Science Journal Classification (ASJC) codes

  • Chemistry(all)
  • Agricultural and Biological Sciences(all)

Cite this

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Synthesis of Versicolorin A by a Mutant Strain of Aspergillus Parasiticus Deficient in Aflatoxin Production. / Lee, Louise S.; Bennett, Joan; Cucullu, Alva F.; Stanley, James B.

In: Journal of Agricultural and Food Chemistry, Vol. 23, No. 6, 01.11.1975, p. 1132-1134.

Research output: Contribution to journalArticle

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T1 - Synthesis of Versicolorin A by a Mutant Strain of Aspergillus Parasiticus Deficient in Aflatoxin Production

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AU - Stanley, James B.

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