Synthesis of Versicolorin A by a Mutant Strain of Aspergillus Parasiticus Deficient in Aflatoxin Production

Louise S. Lee, Joan W. Bennett, Alva F. Cucullu, James B. Stanley

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Abstract

A mutant strain of Aspergillus parasiticus lost its aflatoxin producing ability but produced four yellow pigments. The major one represented 0.13% of the mycelial mass and was identified as versicolorin A by comparison of its physical and chemical properties with those reported for an authentic compound. A trihydroxyanthraquinone, versicolorin A contains the unique difurano group present in aflatoxins and has been proposed as an intermediate in the biosynthesis of these compounds. The isolation and identification of the pigment from mutant A. parasiticus corroborate this theory.

Original languageEnglish (US)
Pages (from-to)1132-1134
Number of pages3
JournalJournal of agricultural and food chemistry
Volume23
Issue number6
DOIs
Publication statusPublished - Nov 1 1975
Externally publishedYes

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All Science Journal Classification (ASJC) codes

  • Chemistry(all)
  • Agricultural and Biological Sciences(all)

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