A systematic procedure to achieve a target crystal size distribution (CSD) under generated operational policies in batch cooling crystallization is presented. An analytical CSD estimator has been employed in the systematic procedure to generate the necessary operational policies to achieve the target CSD. Furthermore, this systematic procedure has been integrated with a generic multi-dimensional model-based framework. The generic nature of the model-based framework allows the study of a wide range of chemical systems under different operational scenarios, enabling thereby, the analysis of various crystallization operations and conditions. Therefore this generic multidimensional model-based framework can be used to generate specific models for crystallization processes and further verify the operational policies generated by the analytical CSD estimator for achieving the targeted CSD consistently. The application of the systematic procedure is illustrated for a potassium dichromate case study.