Tachykinins and neurokinin receptors in bone marrow functions: Neural-hematopoietic link

Tilman E. Klassert, Shyam A. Patel, Pranela Rameshwar

Research output: Contribution to journalReview article

8 Citations (Scopus)

Abstract

After many decades of neuropeptide research, advances in the field of tachykinins have considerably increased and revealed their implications in several physiological processes. In this review we focus on the role of the tachykinins in the regulation of hematopoietic functions. Evidence has shown that neural control of this process is emerging as a significant category in hematopoietic modulation. In the context of this regulation, we discuss the existence of a complex network involving the neurokinin receptors, tachykinins and cytokines. This network is tightly regulated by each of its components.

Original languageEnglish (US)
Pages (from-to)51-61
Number of pages11
JournalJournal of Receptor, Ligand and Channel Research
Volume3
StatePublished - Jun 1 2010

Fingerprint

Tachykinin Receptors
Tachykinins
Bone
Bone Marrow
Physiological Phenomena
Cytokine Receptors
Complex networks
Neuropeptides
Modulation
Research

All Science Journal Classification (ASJC) codes

  • Biophysics
  • Biochemistry
  • Pharmacology
  • Cell Biology

Keywords

  • Crosstalk
  • Hematopoiesis
  • Neurokinin receptor
  • Regulation
  • Tachykinins

Cite this

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abstract = "After many decades of neuropeptide research, advances in the field of tachykinins have considerably increased and revealed their implications in several physiological processes. In this review we focus on the role of the tachykinins in the regulation of hematopoietic functions. Evidence has shown that neural control of this process is emerging as a significant category in hematopoietic modulation. In the context of this regulation, we discuss the existence of a complex network involving the neurokinin receptors, tachykinins and cytokines. This network is tightly regulated by each of its components.",
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Tachykinins and neurokinin receptors in bone marrow functions : Neural-hematopoietic link. / Klassert, Tilman E.; Patel, Shyam A.; Rameshwar, Pranela.

In: Journal of Receptor, Ligand and Channel Research, Vol. 3, 01.06.2010, p. 51-61.

Research output: Contribution to journalReview article

TY - JOUR

T1 - Tachykinins and neurokinin receptors in bone marrow functions

T2 - Neural-hematopoietic link

AU - Klassert, Tilman E.

AU - Patel, Shyam A.

AU - Rameshwar, Pranela

PY - 2010/6/1

Y1 - 2010/6/1

N2 - After many decades of neuropeptide research, advances in the field of tachykinins have considerably increased and revealed their implications in several physiological processes. In this review we focus on the role of the tachykinins in the regulation of hematopoietic functions. Evidence has shown that neural control of this process is emerging as a significant category in hematopoietic modulation. In the context of this regulation, we discuss the existence of a complex network involving the neurokinin receptors, tachykinins and cytokines. This network is tightly regulated by each of its components.

AB - After many decades of neuropeptide research, advances in the field of tachykinins have considerably increased and revealed their implications in several physiological processes. In this review we focus on the role of the tachykinins in the regulation of hematopoietic functions. Evidence has shown that neural control of this process is emerging as a significant category in hematopoietic modulation. In the context of this regulation, we discuss the existence of a complex network involving the neurokinin receptors, tachykinins and cytokines. This network is tightly regulated by each of its components.

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KW - Hematopoiesis

KW - Neurokinin receptor

KW - Regulation

KW - Tachykinins

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JO - Journal of Receptor, Ligand and Channel Research

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