Tamoxifen-induced growth of leiomyomas: A case report

Justin Kang, Laxmi Baxi, Debra Heller

Research output: Contribution to journalArticlepeer-review

23 Scopus citations

Abstract

BACKGROUND: Tamoxifen, a nonsteroidal estrogen agonist-antagonist, is used in the treatment of breast cancer. CASE: A postmenopausal woman, aged 73, while being treated with Tamoxifen, developed continuous growth of her myomatous uterus, became symptomatic and required surgery. CONCLUSION: Tamoxifen at a dose of 40 mg/d has been associated with endometrial carcinoma. The growth of myomas seen with Tamoxifen in this patient seems to be a result of its direct agonist properties.

Original languageEnglish (US)
Pages (from-to)119-120
Number of pages2
JournalJournal of Reproductive Medicine for the Obstetrician and Gynecologist
Volume41
Issue number2
StatePublished - 1996
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Reproductive Medicine
  • Obstetrics and Gynecology

Keywords

  • leiomyoma
  • postmenopause
  • tamoxifen

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