Abstract
Experimental methods and complementary theoretical methods were developed to estimate the two primary biomechanical phenomena with two parameters, for cells in tissue equivalents assuming μ and τ0 were constant in value over time. Temporal data was determined by generating mean squared displacement (MSD) data with a generalized least squares analysis. The FEM was based on the anistropic biphasic theory for tissue equivalents, and was solved with the Control and Optimization (COOPT) software package. COOPT solves a differential-algebraic equation system with piecewise polynomials that were functions of time, allowing the time dependence of 60 for the optimal fit of the compaction data to be obtained.
| Original language | English (US) |
|---|---|
| Pages (from-to) | S-87 |
| Journal | Annals of Biomedical Engineering |
| Volume | 28 |
| Issue number | SUPPL. 1 |
| State | Published - Dec 1 2000 |
| Event | 2000 Annual Fall Meeting of the Biomedical Engineering Society - Washington, WA, USA Duration: Oct 12 2000 → Oct 14 2000 |
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All Science Journal Classification (ASJC) codes
- Biomedical Engineering
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Temporal analysis of fibroblast traction and migration in tissue equivalents. / Shreiber, David; Barocas, Victor; Enever, Paul; Wagle, Mihir; Tranquillo, Robert.
In: Annals of Biomedical Engineering, Vol. 28, No. SUPPL. 1, 01.12.2000, p. S-87.Research output: Contribution to journal › Conference article
TY - JOUR
T1 - Temporal analysis of fibroblast traction and migration in tissue equivalents
AU - Shreiber, David
AU - Barocas, Victor
AU - Enever, Paul
AU - Wagle, Mihir
AU - Tranquillo, Robert
PY - 2000/12/1
Y1 - 2000/12/1
N2 - Experimental methods and complementary theoretical methods were developed to estimate the two primary biomechanical phenomena with two parameters, for cells in tissue equivalents assuming μ and τ0 were constant in value over time. Temporal data was determined by generating mean squared displacement (MSD) data with a generalized least squares analysis. The FEM was based on the anistropic biphasic theory for tissue equivalents, and was solved with the Control and Optimization (COOPT) software package. COOPT solves a differential-algebraic equation system with piecewise polynomials that were functions of time, allowing the time dependence of 60 for the optimal fit of the compaction data to be obtained.
AB - Experimental methods and complementary theoretical methods were developed to estimate the two primary biomechanical phenomena with two parameters, for cells in tissue equivalents assuming μ and τ0 were constant in value over time. Temporal data was determined by generating mean squared displacement (MSD) data with a generalized least squares analysis. The FEM was based on the anistropic biphasic theory for tissue equivalents, and was solved with the Control and Optimization (COOPT) software package. COOPT solves a differential-algebraic equation system with piecewise polynomials that were functions of time, allowing the time dependence of 60 for the optimal fit of the compaction data to be obtained.
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M3 - Conference article
AN - SCOPUS:17144459586
VL - 28
SP - S-87
JO - Annals of Biomedical Engineering
JF - Annals of Biomedical Engineering
SN - 0090-6964
IS - SUPPL. 1
ER -