Temporal analysis of fibroblast traction and migration in tissue equivalents

David Shreiber; Victor Barocas; Paul Enever; Mihir Wagle; Robert Tranquillo

Temporal analysis of fibroblast traction and migration in tissue equivalents

David Shreiber, Victor Barocas, Paul Enever, Mihir Wagle, Robert Tranquillo

Research output: Contribution to journal › Conference article › peer-review

Abstract

Experimental methods and complementary theoretical methods were developed to estimate the two primary biomechanical phenomena with two parameters, for cells in tissue equivalents assuming μ and τ0 were constant in value over time. Temporal data was determined by generating mean squared displacement (MSD) data with a generalized least squares analysis. The FEM was based on the anistropic biphasic theory for tissue equivalents, and was solved with the Control and Optimization (COOPT) software package. COOPT solves a differential-algebraic equation system with piecewise polynomials that were functions of time, allowing the time dependence of 60 for the optimal fit of the compaction data to be obtained.

Original language	English (US)
Pages (from-to)	S-87
Journal	Annals of Biomedical Engineering
Volume	28
Issue number	SUPPL. 1
State	Published - 2000
Externally published	Yes
Event	2000 Annual Fall Meeting of the Biomedical Engineering Society - Washington, WA, USA Duration: Oct 12 2000 → Oct 14 2000

All Science Journal Classification (ASJC) codes

Biomedical Engineering

Cite this

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title = "Temporal analysis of fibroblast traction and migration in tissue equivalents",

abstract = "Experimental methods and complementary theoretical methods were developed to estimate the two primary biomechanical phenomena with two parameters, for cells in tissue equivalents assuming μ and τ0 were constant in value over time. Temporal data was determined by generating mean squared displacement (MSD) data with a generalized least squares analysis. The FEM was based on the anistropic biphasic theory for tissue equivalents, and was solved with the Control and Optimization (COOPT) software package. COOPT solves a differential-algebraic equation system with piecewise polynomials that were functions of time, allowing the time dependence of 60 for the optimal fit of the compaction data to be obtained.",

author = "David Shreiber and Victor Barocas and Paul Enever and Mihir Wagle and Robert Tranquillo",

year = "2000",

language = "English (US)",

volume = "28",

pages = "S--87",

journal = "Annals of Biomedical Engineering",

issn = "0090-6964",

publisher = "Springer Netherlands",

number = "SUPPL. 1",

note = "2000 Annual Fall Meeting of the Biomedical Engineering Society ; Conference date: 12-10-2000 Through 14-10-2000",

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TY - JOUR

T1 - Temporal analysis of fibroblast traction and migration in tissue equivalents

AU - Shreiber, David

AU - Barocas, Victor

AU - Enever, Paul

AU - Wagle, Mihir

AU - Tranquillo, Robert

PY - 2000

Y1 - 2000

N2 - Experimental methods and complementary theoretical methods were developed to estimate the two primary biomechanical phenomena with two parameters, for cells in tissue equivalents assuming μ and τ0 were constant in value over time. Temporal data was determined by generating mean squared displacement (MSD) data with a generalized least squares analysis. The FEM was based on the anistropic biphasic theory for tissue equivalents, and was solved with the Control and Optimization (COOPT) software package. COOPT solves a differential-algebraic equation system with piecewise polynomials that were functions of time, allowing the time dependence of 60 for the optimal fit of the compaction data to be obtained.

AB - Experimental methods and complementary theoretical methods were developed to estimate the two primary biomechanical phenomena with two parameters, for cells in tissue equivalents assuming μ and τ0 were constant in value over time. Temporal data was determined by generating mean squared displacement (MSD) data with a generalized least squares analysis. The FEM was based on the anistropic biphasic theory for tissue equivalents, and was solved with the Control and Optimization (COOPT) software package. COOPT solves a differential-algebraic equation system with piecewise polynomials that were functions of time, allowing the time dependence of 60 for the optimal fit of the compaction data to be obtained.

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M3 - Conference article

AN - SCOPUS:17144459586

SN - 0090-6964

VL - 28

SP - S-87

JO - Annals of Biomedical Engineering

JF - Annals of Biomedical Engineering

IS - SUPPL. 1

T2 - 2000 Annual Fall Meeting of the Biomedical Engineering Society

Y2 - 12 October 2000 through 14 October 2000

ER -

Temporal analysis of fibroblast traction and migration in tissue equivalents

Abstract

All Science Journal Classification (ASJC) codes

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