Thalidomide is a beneficial agent for treating a variety of refractory dermatologic disorders including erythema nodosom leprosum, lupus erythematosus, prurigo nodularis, actinic prurigo, pyoderma gangrenosum and aphthous stomatitis. Two thalidomide analogues, lenalidomide and CC-4047, are considerably more potent with decreased side effects when compared to thalidomide. They are currently undergoing trials and show promise, as they have increased immunomodulatory and anti-angiogenic activity. This category of medication and its use will be reviewed.
|Original language||English (US)|
|Number of pages||6|
|Journal||Acta Dermatovenerologica Croatica|
|State||Published - 2007|
All Science Journal Classification (ASJC) codes
- Infectious Diseases
- Erythema nodosom leprosum