Abstract
Thalidomide is a beneficial agent for treating a variety of refractory dermatologic disorders including erythema nodosom leprosum, lupus erythematosus, prurigo nodularis, actinic prurigo, pyoderma gangrenosum and aphthous stomatitis. Two thalidomide analogues, lenalidomide and CC-4047, are considerably more potent with decreased side effects when compared to thalidomide. They are currently undergoing trials and show promise, as they have increased immunomodulatory and anti-angiogenic activity. This category of medication and its use will be reviewed.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 39-44 |
| Number of pages | 6 |
| Journal | Acta Dermatovenerologica Croatica |
| Volume | 15 |
| Issue number | 1 |
| State | Published - 2007 |
All Science Journal Classification (ASJC) codes
- Medicine(all)
Keywords
- Erythema nodosom leprosum
- Immunomodulation
- Teratogenicity
- Thalidomide