@article{116c6ca3bff14cc892adcee2b75fa0f0,
title = "The Antibacterial Resistance Leadership Group: Progress report and work in progress",
abstract = "The Antibacterial Resistance Leadership Group (ARLG), with funding from the National Institute of Allergy and Infectious Diseases of the National Institutes of Health, was created in June 2013. Its mission is to develop, prioritize, and implement a clinical research agenda that addresses the public health threat of antibacterial resistance. This article reports on the progress that the ARLG has made to date in fulfilling its mission. Since inception, the ARLG has received and reviewed >70 study proposals, initiated >30 studies, executed >300 agreements, included data from >7000 subjects, published >45 manuscripts, and provided opportunities for 26 mentees. Despite this substantial progress, there remains significant work to be accomplished. This article also describes the considerable challenges that lie ahead.",
keywords = "Antibacterial Resistance, Clinical trials, Diagnostics, Network, Stewardship",
author = "Chambers, {Henry F.} and Cross, {Heather R.} and Evans, {Scott R.} and Kreiswirth, {Barry N.} and Fowler, {Vance G.}",
note = "Funding Information: The Antibacterial Resistance Leadership Group (ARLG), with funding from the National Institute of Allergy and Infectious Diseases of the National Institutes of Health, was created in June 2013. Its mission is to develop, prioritize, and implement a clinical research agenda that addresses the public health threat of antibacterial resistance. This article reports on the progress that the ARLG has made to date in fulfilling its mission. Since inception, the ARLG has received and reviewed >70 study proposals, initiated >30 studies, executed >300 agreements, included data from >7000 subjects, published >45 manuscripts, and provided opportunities for 26 mentees. Despite this substantial progress, there remains significant work to be accomplished. This article also describes the considerable challenges that lie ahead. Keywords. antibacterial resistance; network; stewardship; diagnostics; clinical trials. Funding Information: Financial support. This article was supported by the National Institute of Allergy and Infectious Diseases of the NIH (award number UM1AI104681). Supplement sponsorship. This article appears as part of the supplement “Antibacterial Resistance Leadership Group (ARLG): Productivity and Innovation,” sponsored by the Antibacterial Resistance Leadership Group. Funding Information: Potential conflicts of interest. H. F. C. has served on advisory boards for Allergan and Genentech, and has received grant support from The Medicines Company and Genentech. H. R. C.{\textquoteright}s salary is paid by an ARLG grant. S. R. E. has received grants from NIAID/NIH and Fogarty and has received personal fees from the American Statistical Association, Society for Clinical Trials, Drug Information Association, US Food and Drug Administration, NIH, City of Hope, Huntington{\textquoteright}s Study Group, IMMPACT, PPRECISE, Muscle Study Group, DeGruyter (Statistical Communications in Infectious Diseases), Takeda, Pfizer, Roche, Novartis, Merck, Achaogen, Auspex, Alcon, Chelsea, Mannkind, QRx Pharma, Genentech, Affymax, FzioMed, Amgen, GSK, Sunovion, Boehringer-Ingelheim, Cubist, AstraZeneca, Teva, Repros, Dexcom, Zeiss, University of Rhode Island, New Jersey Medical School–Rutgers, University of Vermont, Osaka University, and the National Cerebral and Cardiovascular Center of Japan. V. G. F. has received grants from NIH, MedImmune, Cerexa/Forest/Actavis/Allergan, Pfizer, Advanced Liquid Logics, Theravance, Novartis, Cubist/Merck, Medical Biosurfaces, Locus, Affinergy, Contrafect, Karius, and the Centers for Disease Control and Prevention; has received personal fees from Merck, Pfizer, Novartis, Galderma, Novadigm, Durata, Debiopharm, Genentech, Achaogen, Affinium, The Medicines Company, Cerexa, Tetraphase, Trius, MedImmune, Bayer, Theravance, Cubist, Basilea, Affinergy, Janssen, Contrafect, xBiotech, Green Cross, Cubist, and UpToDate; and has a patent pending for sepsis diagnostics. B. N. K. reports no potential conflicts. The authors have submitted the ICMJE Form for Disclosure of Potential Conflicts of Interest. Conflicts that the editors consider relevant to the content of the manuscript have been disclosed. Publisher Copyright: {\textcopyright} The Author 2017.",
year = "2017",
doi = "10.1093/cid/ciw824",
language = "English (US)",
volume = "64",
pages = "S3--S7",
journal = "Clinical Infectious Diseases",
issn = "1058-4838",
publisher = "Oxford University Press",
}