The effect of Escherichia coli endotoxin on the plasma iron concentration in the domestic fowl

E. J. Butler, M. J. Curtis, Malcolm Watford

Research output: Contribution to journalArticle

16 Citations (Scopus)

Abstract

The intravenous injection of OIII:B4 endotoxin rapidly produced a transient hypoferremia in 8-12 week old pathogen free chickens. This response was maximal after 12-16 hr, was dose dependent and was superimposed on a diurnal variation in the plasma iron level. Recovery was also rapid and may have been facilitated by the simultaneous increase in the activity of ceruloplasmin which is believed to promote the transference of iron from the reticuloendothelial and hepatic cells to the plasma.

Original languageEnglish (US)
Pages (from-to)267-269
Number of pages3
JournalResearch in Veterinary Science
Volume15
Issue number2
StatePublished - Dec 1 1973

Fingerprint

Poultry
endotoxins
Iron
iron
chickens
Escherichia coli
ferroxidase
Ceruloplasmin
diurnal variation
intravenous injection
Endotoxins
Intravenous Injections
hepatocytes
Hepatocytes
Chickens
pathogens
dosage
Escherichia coli endotoxin

All Science Journal Classification (ASJC) codes

  • veterinary(all)

Cite this

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The effect of Escherichia coli endotoxin on the plasma iron concentration in the domestic fowl. / Butler, E. J.; Curtis, M. J.; Watford, Malcolm.

In: Research in Veterinary Science, Vol. 15, No. 2, 01.12.1973, p. 267-269.

Research output: Contribution to journalArticle

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