The effect of hysterectomy on hormone-induced lordosis behavior in hamsters

Harold I. Siegel, Pieta Cohen, Jay S. Rosenblatt

Research output: Contribution to journalArticle

5 Scopus citations

Abstract

Ovariectomized-hysterectomized (OH) and ovariectomized-sham hysterectomized (OSH) hamsters were tested for lordosis behavior following treatments including either 1, 5, or 10 μg estradiol benzoate (EB) in combination with 0.1, 0.25, and 0.5 mg progesterone. Few animals responded at the 1 μg dose of EB and there were no differences in latency to the first display of lordosis or in the total lordosis duration among responding animals in the 5 and 10 μg EB groups. However, there was significantly more positive tests in the OSH group injected with 5 μg EB than in the OH group and this difference approached statistical significance in the 10 μg EB groups. The results are compared to similar studies in rats and possible mechanisms for the effects of hysterectomy are discussed.

Original languageEnglish (US)
Pages (from-to)851-853
Number of pages3
JournalPhysiology and Behavior
Volume23
Issue number5
DOIs
StatePublished - Nov 1979

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All Science Journal Classification (ASJC) codes

  • Experimental and Cognitive Psychology
  • Behavioral Neuroscience

Keywords

  • Estrogen
  • Hamster
  • Hysterectomy
  • Lordosis
  • Progesterone

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