A retrospective cohort study using 1980-1984 Medicaid billing data from 3 US states was performed to assess the relative risk of hypersensitivity reactions from different nonsteroidal antiinflammatory drugs (NSAID). Comparing tolmetin sodium to other NSAID, pooling the data across the 3 US states using the Mantel-Haenszel procedure, gave an overall relative risk (95% confidence interval) of 1.1 (0.8-1.4). After adjusting from multiple potential confounding variables using logistic regression, an odds ratio (95% confidence interval) of 0.9 (0.6-1.2) was observed. These data do no confirm previous suggestions that use of tolmetin is associated with a higher risk of hypersensitivity reaction than use of other NSAID.
|Original language||English (US)|
|Number of pages||5|
|Journal||Journal of Rheumatology|
|State||Published - 1988|
All Science Journal Classification (ASJC) codes
- Immunology and Allergy