The effect of indication on the risk of hypersensitivity reactions associated with tolmetin sodium vs other nonsteroidal antiinflammatory drugs

B. L. Strom, J. L. Carson, R. Schinnar, E. Sim, M. L. Morse

Research output: Contribution to journalArticlepeer-review

24 Scopus citations

Abstract

A retrospective cohort study using 1980-1984 Medicaid billing data from 3 US states was performed to assess the relative risk of hypersensitivity reactions from different nonsteroidal antiinflammatory drugs (NSAID). Comparing tolmetin sodium to other NSAID, pooling the data across the 3 US states using the Mantel-Haenszel procedure, gave an overall relative risk (95% confidence interval) of 1.1 (0.8-1.4). After adjusting from multiple potential confounding variables using logistic regression, an odds ratio (95% confidence interval) of 0.9 (0.6-1.2) was observed. These data do no confirm previous suggestions that use of tolmetin is associated with a higher risk of hypersensitivity reaction than use of other NSAID.

Original languageEnglish (US)
Pages (from-to)695-699
Number of pages5
JournalJournal of Rheumatology
Volume15
Issue number4
StatePublished - 1988

All Science Journal Classification (ASJC) codes

  • Rheumatology
  • Immunology and Allergy
  • Immunology

Fingerprint Dive into the research topics of 'The effect of indication on the risk of hypersensitivity reactions associated with tolmetin sodium vs other nonsteroidal antiinflammatory drugs'. Together they form a unique fingerprint.

Cite this