The effects of molecular weight on viability within PEGDA hydrogel microspheres

  • Ron Falkowski
  • , Michael Medini
  • , Ronke Olabisi

Research output: Chapter in Book/Report/Conference proceedingConference contribution

1 Scopus citations

Abstract

Poly(ethylene glycol) diacrylate (PEGDA) is a polymer often used in tissue engineering as a hydrogel scaffold. We determined the cell viability of murine osteoblast cells microencapsulated in PEGDA hydrogels of various molecular weights. Microspheres ranged between 20-200 μm in radius, to avoid exceeding the diffusion limit of oxygen. Concurrent diffusion studies were performed for each molecular weight to assess the size of the molecules permitted access by the hydrogels. Results demonstrated higher cell viability in higher molecular weight PEGDA microspheres.

Original languageEnglish (US)
Title of host publicationProceedings - 2014 40th Annual Northeast Bioengineering Conference, NEBEC 2014
PublisherInstitute of Electrical and Electronics Engineers Inc.
ISBN (Electronic)9781479937288
DOIs
StatePublished - Dec 2 2014
Event2014 40th Annual Northeast Bioengineering Conference, NEBEC 2014 - Boston, United States
Duration: Apr 25 2014Apr 27 2014

Publication series

NameProceedings of the IEEE Annual Northeast Bioengineering Conference, NEBEC
Volume2014-December
ISSN (Print)1071-121X
ISSN (Electronic)2160-7001

Other

Other2014 40th Annual Northeast Bioengineering Conference, NEBEC 2014
Country/TerritoryUnited States
CityBoston
Period4/25/144/27/14

All Science Journal Classification (ASJC) codes

  • Bioengineering

Keywords

  • Cell encapsulation
  • Hydrogel
  • Microspheres
  • Tissue engineering

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